منابع مشابه
Termination of Pregnancy with Prostaglandin
تاثیر تزریق داخل رحمی apGF2 و تزریق داخل وریدی اکسی توسین به عنوان دو روش درمانی در ختم حاملگی، در زنانی که در سه ماهه دوم بارداری دچار پارگی کیسه آب بودند، با یک دیگر مقایسه شده اند.
متن کاملInteraction of adrenergic antagonists with prostaglandin E2 and tetrahydrocannabinol in the eye.
Both alpha- and beta-adrenergic antagonists have been utilized in an atempt to discern the site of action of prostaglandin (PG) and tetrahydrocannabinol (THC) in the eye. Both alpha- and beta-adrenergic antagonists (alpha-antagonists, phentolamine and phenoxybenzamine; beta-antagonists, propranolol and sotalol) cuased a dose-dependent reduction in intraocular pressure and blood pressure and inc...
متن کاملOn the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2.
Chemoattractant receptor-homologous molecule expressed on T helper 2 cells (CRTH2) has attracted interest as a potential therapeutic target in inflammatory diseases. Ramatroban, a thromboxane A2 receptor antagonist with clinical efficacy in allergic rhinitis, was recently found to also display potent CRTH2 antagonistic activity. Here, we present the pharmacological profile of three ramatroban a...
متن کاملClinical pharmacology of calcium antagonists. Satellite symposium on calcium antagonists.
A new class of agents has been made available for the treatment of hypertension. These calcium antagonists have rapid bioavailability and dramatic antihypertensive effects through reduction of total peripheral resistance and the vascular resistance of the major target organs of the body. These changes are usually associated with unchanged cardiac output, preserved organ blood flows, maintained ...
متن کاملLead Optimization Studies of Cinnamic Amide EP2 Antagonists
Prostanoid receptor EP2 can play a proinflammatory role, exacerbating disease pathology in a variety of central nervous system and peripheral diseases. A highly selective EP2 antagonist could be useful as a drug to mitigate the inflammatory consequences of EP2 activation. We recently identified a cinnamic amide class of EP2 antagonists. The lead compound in this class (5d) displays anti-inflamm...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1971
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1971.tb07142.x